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Medical cannabis

Section Editor: [position vacant] Submissions handled by Editor-in-Chief
Covers therapeutic uses of cannabis and cannabinoids (plant-derived and synthetic) for any medical or psychological condition in humans and animals.

  1. Cancer comes in second place on the list of causes of death worldwide. In 2018, the 5-year prevalence of breast cancer (BC), prostate cancer (PC), and colorectal cancer (CRC) were 30%, 12.3%, and 10.9%, respec...

    Authors: Husam A. ALSalamat, Sara Feras Abuarab, Hazem Mohamed Salamah, Anas Hasan Ishqair, Mohammad Fuad Dwikat, Anas Zakarya Nourelden, Aseel N. Qandil, Yasmeen Barakat and Muna Barakat
    Citation: Journal of Cannabis Research 2024 6:24
  2. Medical cannabis, legalized in many countries, remains illegal in France. Despite an experiment in the medical use of cannabis that began in March 2021 in France, little is known about the factors associated w...

    Authors: Solène Wallez, Isabelle Kousignian, Irwin Hecker, Selma Faten Rezag Bara, Astrid Juhl Andersen, Maria Melchior, Jean-Sébastien Cadwallader and Murielle Mary-Krause
    Citation: Journal of Cannabis Research 2024 6:19
  3. Prior reports indicate that modulation of the endocannabinoid system (ECS) may have a protective benefit for Covid-19 patients. However, associations between cannabis use (CU) or CU not in remission (active ca...

    Authors: Joseph-Kevin Igwe and Ugo Alaribe
    Citation: Journal of Cannabis Research 2024 6:18
  4. The underlying neurobiological mechanisms of cannabidiol’s (CBD) management of alcohol use disorder (AUD) remains elusive.

    Authors: Tristan Hurzeler, Joshua Watt, Warren Logge, Ellen Towers, Anastasia Suraev, Nicholas Lintzeris, Paul Haber and Kirsten C. Morley
    Citation: Journal of Cannabis Research 2024 6:15
  5. In animals, the endocannabinoid system regulates multiple physiological functions. Like humans, animals respond to preparations containing phytocannabinoids for treating several conditions. In Argentina, laws ...

    Authors: Diana Banach and Paola Ferrero
    Citation: Journal of Cannabis Research 2023 5:39
  6. Medical cannabis (MC) is increasingly used for chronic pain, but it is unclear how it aids in pain management. Previous literature suggests that MC could holistically alter the pain experience instead of only ...

    Authors: Jussi Jylkkä, Aleksi Hupli, Aleksandra Nikolaeva, Sandra Alanen, Anna Erika Back, Sara Lindqvist, Andreas Krabbe, Maya Lavie-Ajayi and Oskari Kantonen
    Citation: Journal of Cannabis Research 2023 5:38
  7. Road safety is an important concern amidst expanding worldwide access to legal cannabis. The present study reports on the driving-related subsection of the Cannabis as Medicine Survey 2020 (CAMS-20) which surv...

    Authors: Thomas R. Arkell, Sarah V. Abelev, Llewellyn Mills, Anastasia Suraev, Jonathon C. Arnold, Nicholas Lintzeris and Iain S. McGregor
    Citation: Journal of Cannabis Research 2023 5:35
  8. Since 2001, Canadians have been able to obtain cannabis for medical purposes, initially through the Access to Cannabis for Medical Purposes Regulations (ACMPR). The Cannabis Act (Bill C-45) came into force on ...

    Authors: Cecilia Costiniuk, Caroline A. MacCallum, Michael Boivin, Sergio Rueda, Gary Lacasse, Zach Walsh, Paul J. Daeninck, Shari Margolese, Enrico Mandarino, Jagpaul Kaur Deol, Tatiana Sanchez and Alan D. Bell
    Citation: Journal of Cannabis Research 2023 5:25
  9. Substance administration to laboratory animals necessitates careful consideration and planning in order to enhance agent distribution while reducing any harmful effects from the technique. There are numerous m...

    Authors: Kaveh Momenzadeh, Diana Yeritsyan, Nadim Kheir, Rosalyn M. Nazarian and Ara Nazarian
    Citation: Journal of Cannabis Research 2023 5:24
  10. The COVID-19 pandemic disrupted health care but it is unknown how it impacted the lives of people using medical cannabis for chronic pain.

    Authors: Yuval Zolotov, Jacinta Lomba, Megan Ghiroli, Mariya Masyukova, Julia H. Arnsten, Joanna L. Starrels, Jonathan Ross, Chinazo O. Cunningham and Deepika E. Slawek
    Citation: Journal of Cannabis Research 2023 5:10
  11. Little is known about the frequency with which different combinations of phytochemicals (chemovars) arise in Cannabis flower or whether common chemovars are associated with distinct pharmacodynamics and patient h...

    Authors: Jacob Miguel Vigil, Sarah See Stith, Franco Brockelman, Keenan Keeling and Branden Hall
    Citation: Journal of Cannabis Research 2023 5:4
  12. The medicinal effects of cannabis varieties on the market cannot be explained solely by the presence of the major cannabinoids Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD). Evidence for putative entourage ...

    Authors: Monique van Es-Remers, Jesus Arellano Spadaro, Eefje Poppelaars, Hye Kyong Kim, Marieke van Haaster, Marcel de Wit, Eva ILiopoulou, Marjolein Wildwater and Henrie Korthout
    Citation: Journal of Cannabis Research 2022 4:53
  13. Use of medical cannabis is increasing among older adults. However, few investigations have examined cannabis use in this population.

    Authors: Laura MacNair, Maja Kalaba, Erica N. Peters, Matthew T. Feldner, Graham M. L. Eglit, Lucile Rapin, Cynthia El Hage, Erin Prosk and Mark A. Ware
    Citation: Journal of Cannabis Research 2022 4:50
  14. Few studies have evaluated weight change in patients who initiate medical marijuana treatment to address diagnosed health concerns. The objective of this study was to examine whether patients initiating medica...

    Authors: Michelle R. Lent, Meghan Visek, Paulina Syracuse, Karen L. Dugosh and David S. Festinger
    Citation: Journal of Cannabis Research 2022 4:48
  15. While cannabis is known to have immunomodulatory properties, the clinical consequences of its use on outcomes in COVID-19 have not been extensively evaluated. We aimed to assess whether cannabis users hospital...

    Authors: Carolyn M. Shover, Peter Yan, Nicholas J. Jackson, Russell G. Buhr, Jennifer A. Fulcher, Donald P. Tashkin and Igor Barjaktarevic
    Citation: Journal of Cannabis Research 2022 4:46
  16. In 2019, Thailand legalized cannabidiol (CBD) for intractable epilepsy. The purpose of this study was to collect information regarding the experience and knowledge of CBD use in pediatric epilepsy. To the best...

    Authors: Monsicha Ngampoopun, Charcrin Nabangchang and Piradee Suwanpakdee
    Citation: Journal of Cannabis Research 2022 4:43
  17. Patients use medical cannabis for a wide array of illnesses and symptoms, and many substitute cannabis for pharmaceuticals. This substitution often occurs without physician oversight, raising patient safety co...

    Authors: Alexis Holman, Daniel J. Kruger, Philippe Lucas, Kaye Ong, Rachel S. Bergmans and Kevin F. Boehnke
    Citation: Journal of Cannabis Research 2022 4:32
  18. Purified cannabidiol (CBD), a non-psychoactive phytocannabinoid, has gained regulatory approval to treat intractable childhood epilepsies. Despite this, artisanal and commercial CBD-dominant hemp-based product...

    Authors: Carol J. Milligan, Lyndsey L. Anderson, Michael T. Bowen, Samuel D. Banister, Iain S. McGregor, Jonathon C. Arnold and Steven Petrou
    Citation: Journal of Cannabis Research 2022 4:30
  19. The legalization of hemp in the USA has led to tremendous growth in the availability of hemp-derived products, particularly cannabidiol (CBD) products. The lack of regulatory oversight in this industry has res...

    Authors: Erin Johnson, Michael Kilgore and Shanna Babalonis
    Citation: Journal of Cannabis Research 2022 4:28
  20. Cannabis is increasingly used for medical purposes, particularly in countries like Canada where cannabis was recently legalized for recreational use. We aimed to assess self-medication with cannabis post-canna...

    Authors: Antoine Asselin, Olivier Beauparlant Lamarre, Richard Chamberland, Sarah-Jeanne McNeil, Eric Demers and Arsène Zongo
    Citation: Journal of Cannabis Research 2022 4:26
  21. The main biological activities of cannabis are due to the presence of several compounds known as cannabinoids. Delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are two of the main cannabinoids. Studies...

    Authors: Tameika R. James, Andrea A. Richards, Dwight A. Lowe, Walton A. Reid, Charah T. Watson and Dagogo J. Pepple
    Citation: Journal of Cannabis Research 2022 4:15
  22. We undertook this systematic review to determine the efficacy and safety of cannabis-based medicine as a treatment for behavioral, psychological, and motor symptoms associated with neurocognitive disorders.

    Authors: Anees Bahji, Natasha Breward, Whitney Duff, Nafisa Absher, Scott B. Patten, Jane Alcorn and Darrell D. Mousseau
    Citation: Journal of Cannabis Research 2022 4:11
  23. The wide heterogeneity of available cannabis products makes it difficult for physicians to appropriately guide patients. In the current study, our objective was to characterize naturalistic cannabis use routin...

    Authors: Kevin F. Boehnke, Laura Yakas, J. Ryan Scott, Melissa DeJonckheere, Evangelos Litinas, Suzanne Sisley, Daniel J. Clauw, David A. Williams and Jenna McAfee
    Citation: Journal of Cannabis Research 2022 4:7
  24. A case of an 85-year-old patient with concurrent use of warfarin and medical cannabis containing delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) is described. Warfarin continues to be a cornerstone of...

    Authors: Tyan F. Thomas, Evdokia S. Metaxas, Thu Nguyen, Whitni Bennett, Kathryn V. Skiendzielewski, Diane H. Quinn and Alice L. Scaletta
    Citation: Journal of Cannabis Research 2022 4:6
  25. Palliative care aims to improve quality of life through optimal symptom control and pain management. Cannabis-based medicinal products (CBMPs) have a proven role in the treatment of chemotherapy-induced nausea an...

    Authors: Devaki Nimalan, Michal Kawka, Simon Erridge, Mehmet Ergisi, Michael Harris, Oliver Salazar, Rayyan Ali, Katerina Loupasaki, Carl Holvey, Ross Coomber, Michael Platt, James J. Rucker, Shaheen Khan and Mikael H. Sodergren
    Citation: Journal of Cannabis Research 2022 4:3
  26. Recently, the renewed global interest in cannabis’ therapeutic properties has resulted in shifting attitudes and legislative policies worldwide. The aim of this systematic review is to explore the existing lit...

    Authors: Jared M. Weisman and Marcus Rodríguez
    Citation: Journal of Cannabis Research 2021 3:47
  27. Chronic musculoskeletal pain (CMP) may lead to reduced physical function and is the most common cause of chronic non-cancer pain. Currently, the pharmacotherapeutic options against CMP are limited and frequent...

    Authors: Daniela Furrer, Edeltraut Kröger, Martine Marcotte, Nathalie Jauvin, Richard Bélanger, Mark Ware, Guillaume Foldes-Busque, Michèle Aubin, Pierre Pluye and Clermont E. Dionne
    Citation: Journal of Cannabis Research 2021 3:41
  28. Cannabinoids are increasingly becoming compounds of medical interest. However, cannabis plants only produce carboxylated cannabinoids. In order to access the purported medical benefits of these compounds, the ...

    Authors: Kenneth J. Olejar and Chad A. Kinney
    Citation: Journal of Cannabis Research 2021 3:40
  29. Since the legalization of medical marijuana (MMJ) in Ohio in 2018, many chronic pain (CP) patients have become interested in it as an alternative or adjunct to prescription opioids. This has not only created a...

    Authors: Daniel Adams, Nana Ama Ofei-Tenkorang, Patrick Connell, Alexa Owens, Aaron Gothard, Dmitri Souza and Samer Narouze
    Citation: Journal of Cannabis Research 2021 3:37
  30. Despite repeated calls by medical associations to gather evidence on the harms and benefits of cannabis, there are ongoing methodological challenges to conducting observational and clinical studies on cannabis...

    Authors: Philippe Lucas, Susan Boyd, M.-J. Milloy and Zach Walsh
    Citation: Journal of Cannabis Research 2021 3:34
  31. With millions of people using cannabinoids to treat a host of medical conditions, clinicians want guidance on how to utilize cannabinoids as pharmacotherapy in their practices. The Delphi method is a systemati...

    Authors: Kevin P. Hill and Donald I. Abrams
    Citation: Journal of Cannabis Research 2021 3:23

    The original article was published in Journal of Cannabis Research 2021 3:22

    The Commentary to this article has been published in Journal of Cannabis Research 2021 3:24

  32. Globally, medical cannabis legalization has increased in recent years and medical cannabis is commonly used to treat chronic pain. However, there are few randomized control trials studying medical cannabis ind...

    Authors: Arun Bhaskar, Alan Bell, Michael Boivin, Wellington Briques, Matthew Brown, Hance Clarke, Claude Cyr, Elon Eisenberg, Ricardo Ferreira de Oliveira Silva, Eva Frohlich, Peter Georgius, Malcolm Hogg, Tina Ingrid Horsted, Caroline A. MacCallum, Kirsten R. Müller-Vahl, Colleen O’Connell…
    Citation: Journal of Cannabis Research 2021 3:22

    The Commentary to this article has been published in Journal of Cannabis Research 2021 3:23

  33. Cannabidiol (CBD) is a primary component in the cannabis plant; however, in recent years, interest in CBD treatments has outpaced scientific research and regulatory advancement resulting in a confusing landsca...

    Authors: Lucile Rapin, Rihab Gamaoun, Cynthia El Hage, Maria Fernanda Arboleda and Erin Prosk
    Citation: Journal of Cannabis Research 2021 3:19
  34. People report using cannabis as a substitute for prescription medications but may be doing so without the knowledge of their primary health care providers (PCPs). This lack of integration creates serious conce...

    Authors: Kevin F. Boehnke, Evangelos Litinas, Brianna Worthing, Lisa Conine and Daniel J. Kruger
    Citation: Journal of Cannabis Research 2021 3:2
  35. With the improvement in modern medicine, the world’s human and feline (Felis catus, the domestic cat) population is aging. As the population grows older, there is an increase of age-related diseases, such as Alzh...

    Authors: Lilach Zadik-Weiss, Sivan Ritter, Vered Hermush, Nethanel Asher, Avi Avital and Reuven Or
    Citation: Journal of Cannabis Research 2020 2:43
  36. Social media and academic literature suggest that more people are using cannabis to treat their own or their dog’s chronic pain. This study identifies the reasons people use cannabis products to treat their ow...

    Authors: Jean E. Wallace, Lori R. Kogan, Eloise C. J. Carr and Peter W. Hellyer
    Citation: Journal of Cannabis Research 2020 2:36

    The Publisher Correction to this article has been published in Journal of Cannabis Research 2020 2:40

  37. Around 144 cannabinoids have been identified in cannabis plant, among them tetrahydrocannabinol (THC) and cannabidiol (CBD) are the most prominent ones. Because of the legal restrictions on cannabis in many co...

    Authors: Masoumeh Pourseyed Lazarjani, Stephanie Torres, Thom Hooker, Chris Fowlie, Owen Young and Ali Seyfoddin
    Citation: Journal of Cannabis Research 2020 2:35
  38. Growing interest in the medicinal properties of cannabis has led to an increase in its use to treat medical conditions, and the establishment of state-specific medical cannabis programs. Despite medical cannab...

    Authors: V. Kishan Mahabir, Jamil J. Merchant, Christopher Smith and Alisha Garibaldi
    Citation: Journal of Cannabis Research 2020 2:32
  39. Terpenes contribute to the pharmacology, efficacy, aroma, and flavor of cannabis inflorescence, improving the experience for medical and recreational users. Terpenes are inherently volatile, resulting in the l...

    Authors: Justin Bueno, Emily Leuer, Michael Kearney Jr, Edward H. Green and Eric A. Greenbaum
    Citation: Journal of Cannabis Research 2020 2:27
  40. Δ9-Tetrahydrocannabivarin (THCV) is a cannabis-derived compound with unique properties that set it apart from the more common cannabinoids, such as Δ9-tetrahydrocannabinol (THC). The main advantage of THCV ove...

    Authors: Amos Abioye, Oladapo Ayodele, Aleksandra Marinkovic, Risha Patidar, Adeola Akinwekomi and Adekunle Sanyaolu
    Citation: Journal of Cannabis Research 2020 2:6