Table 1 Characteristics of TEMPO cohort participants included in the study by reason for cannabis use

Sociodemographic characteristics

 Sex

0.960

  Female

212 (61.4%)

190 (61.5%)

22 (61.1%)

  Male

133 (38.6%)

119 (38.5%)

14 (38.9%)

Age, median (IQR)

41.1 (38.4, 43.5)

41.1 (38.5, 43.5)

40.7 (37.8, 42.6)

0.335

 Marital status

0.550

  Married, in civil union, in relationship

289 (84.0%)

260 (84.4%)

29 (80.6%)

  Single, divorced, widowed

55 (16.0%)

48 (15.6%)

7 (19.4%)

Having children

263 (76.7%)

240 (78.2%)

23 (63.9%)

0.055

 Socioeconomic position

0.005

  Intermediate or high

242 (71.8%)

224 (74.2%)

18 (51.4%)

  Lower

95 (28.2%)

78 (25.8%)

17 (48.6%)

Cannabis use

 Current or former cannabis use

 < 0.001

  Experimenters (at least once in lifetime)

267 (80.4%)

254 (85.5%)

13 (37.1%)

  Used in the past year

28 (8.4%)

22 (7.4%)

6 (17.1%)

  Use in the past month

37 (11.1%)

21 (7.1%)

16 (45.7%)

 Cannabis use trajectory

 < 0.001

  Experimentation

261 (76.5%)

246 (80.7%)

15 (41.7%)

  Decreasing consumption

55 (16.1%)

43 (14.1%)

12 (33.3%)

  High consumption

25 (7.3%)

16 (5.2%)

9 (25.0%)

High risk of problematic cannabis use³

22 (7.5%)

11 (4.2%)

11 (33.3%)

 < 0.001

 Age of onset cannabis

0.081

  Late initiation (after 16 years)

240 (70.0%)

220 (71.4%)

20 (57.1%)

  Early initiation (16 years old and under)

103 (30.0%)

88 (28.6%)

15 (42.9%)

Using cannabis alone

50 (14.7%)

29 (9.5%)

21 (58.3%)

 < 0.001

Mental health

 Anxiety

40 (11.6%)

32 (10.4%)

8 (22.2%)

0.051

 Depression

46 (13.4%)

36 (11.7%)

10 (27.8%)

0.016

 Internalized disorders

43 (12.6%)

35 (11.5%)

8 (22.2%)

0.105

Physical health

 Overweight or obesity

49 (14.6%)

40 (13.3%)

9 (25.7%)

0.049

 Chronic digestive disease

12 (3.6%)

10 (3.3%)

2 (6.1%)

0.337

 Cancer

7 (2.1%)

6 (2.0%)

1 (3.0%)

0.522

 Asthma

30 (9.0%)

27 (9.0%)

3 (9.1%)

1.000

 Migraines

56 (16.8%)

49 (16.3%)

7 (21.2%)

0.471

 Nervous breakdown

48 (14.5%)

40 (13.4%)

8 (25.0%)

0.107

 Musculoskeletal disorders

104 (31.3%)

86 (29.0%)

18 (51.4%)

0.007

 Arthritis

35 (10.4%)

32 (10.6%)

3 (9.1%)

1.000

 High blood pressure

16 (4.7%)

14 (4.6%)

2 (5.9%)

0.669

 Insomnia

48 (14.5%)

38 (12.8%)

10 (29.4%)

0.017

 Crohn’s disease

12 (3.6%)

9 (3.0%)

3 (9.1%)

0.103

 Multiple sclerosis

2 (0.6%)

1 (0.3%)

1 (3.0%)

0.188

 Post-traumatic stress disorder

8 (2.4%)

6 (2.0%)

2 (6.1%)

0.179

 Cranial trauma

16 (4.8%)

14 (4.7%)

2 (6.1%)

0.666

Use of psychoactive substances

 Smoking status

0.001

  Non-smoker

135 (40.8%)

130 (44.1%)

5 (13.9%)

  Regular, occasional or ex-smoker

196 (59.2%)

165 (55.9%)

31 (86.1%)

 Age of smoking initiation

0.022

  Late initiation (after 14 years old)

192 (62.1%)

177 (64.4%)

15 (44.1%)

  Early initiation (14 years old and under)

117 (37.9%)

98 (35.6%)

19 (55.9%)

 Alcohol consumption

0.205

  Never, once a month or less

80 (23.3%)

69 (22.5%)

11 (30.6%)

  2 to 4 times a month

105 (30.6%)

96 (31.3%)

9 (25.0%)

  2 to 3 times a week

93 (27.1%)

87 (28.3%)

6 (16.7%)

  4 times a week or more

65 (19.0%)

55 (17.9%)

10 (27.8%)

 Other drugs lifetime use⁴

0.045

  No, never

268 (78.8%)

245 (80.3%)

23 (65.7%)

  Yes, at least once

72 (21.2%)

60 (19.7%)

12 (34.3%)

Negative events during childhood

 Repeating a grade

162 (49.2%)

142 (48.3%)

20 (57.1%)

0.323

 Violence during childhood

128 (41.2%)

110 (39.6%)

18 (54.5%)

0.098

Parental characteristics

 Tobacco parents

0.194

  Non-smoker

93 (27.2%)

87 (28.4%)

6 (16.7%)

  Former-smoker

129 (37.7%)

111 (36.3%)

18 (50.0%)

  Smoker

120 (35.1%)

108 (35.3%)

12 (33.3%)

 Alcohol parents

0.002

  Non-unhealthy alcohol use

237 (69.3%)

220 (71.9%)

17 (47.2%)

  Unhealthy alcohol use

105 (30.7%)

86 (28.1%)

19 (52.8%)

 Parental divorce before 17 years old

18 (5.3%)

12 (3.9%)

6 (16.7%)

0.007

 Parental depression before 17 years old

39 (11.4%)

31 (10.1%)

8 (22.2%)

0.047