Table 3 Logistic regression models for the association between recreation, medical or both types of marijuana use vs. no marijuana use and odds of receiving ≥50 MME prescription opioid dose

Model 1: Unadjusted

OR (95%CI)

Model 2: Demographics

OR (95%CI)

Model 3: MH and SUD

OR (95%CI)

Model 4: Full Adjusted Model

OR (95%CI)

Marijuana Use

 No Marijuana

1.0

1.0

1.0

1.0

 Recreational Only

0.97 (0.62-1.53)

0.90 (0.56-1.43)

0.88 (0.54-1.45)

1.00 (0.59-1.70)

 Medical only

0.63 (0.30-1.31)

0.54 (0.25-1.17)

0.51 (0.23-1.12)

0.52 (0.23-1.16)

 Both

0.92 (0.60-1.39)

0.81 (0.52-1.26)

0.76 (0.48-1.22)

0.79 (0.48-1.31)

Age

0.99 (0.97-1.00)

0.99 (0.98-1.01)

0.99 (0.97-1.01)

Male gender

1.42 (0.99-2.04)

1.46 (1.01-2.12)

1.38 (0.93-2.03)

Race

 White

1.0

1.0

1.0

 Black

0.57 (0.35-0.93)

0.59 (0.36-0.97)

0.58 (0.34-0.99)

 Other

1.38 (0.50-3.80)

1.65 (0.58-4.69)

1.42 (0.47-4.27)

Marital Status

 Married/ live with partner

1.0

1.0

1.0

 Widow/Div/Sep

1.12 (0.75-1.69)

1.05 (0.69-1.59)

1.14 (0.73-1.78)

 Never married

1.11 (0.66-1.87)

1.07 (0.63-1.82)

1.20 (0.68-2.09)

Lifetime Depression

0.96 (0.61-1.49)

0.72 (0.44-1.18)

Anxiety^a

2.04 (1.22-3.41)

1.48 (0.83-2.62)

PTSD^b

0.97 (0.56-1.70)

0.87 (0.48-1.59)

Anhedonia

0.73 (0.47-1.12)

0.72 (0.44-1.18)

Recreational vs. no marijuana

OR (95%CI)

Medical vs. no marijuana

OR (95%CI)

Both medical and recreational vs. no marijuana

OR (95%CI)

Model 4: Full Adjusted Model

OR (95%CI)

Any SUD^c

1.24 (0.73-2.10)

1.10 (0.63-1.92)

Current Smoker

0.99 (0.65-1.52)

1.00 (0.63-1.57)

High pain severity

0.95 (0.60-1.51)

High pain interference

1.82 (1.18-2.81)

# Pain Sites

0.96 (0.91-1.02)

COMM^d

0.88 (0.55-1.41)

PODS^e

3.08 (1.96-4.84)

Vital Exhaustion

1.25 (0.68-2.30)

High Emotional Support^f

0.70 (0.46-1.04)

High Social Role Functioning^g

1.10 (0.59-2.05)