Table 2 Logistic regression models for the association between recreation, medical or both types of marijuana use vs. no marijuana use and odds of daily prescription opioid use

Model 1: Unadjusted

OR (95%CI)

Model 2: Demographics

OR (95%CI)

Model 3: MH and SUD

OR (950025CI)

Model 4: Full Adjusted Model

OR (95%CI)

Marijuana Use

 No Marijuana

1.0

1.0

1.0

1.0

 Recreational Only

1.58 (1.11-2.26)

1.70 (1.13-2.55)

1.34 (0.87-2.07)

1.61 (1.02-2.54)

 Medical only

1.39 (0.83-2.35)

1.11 (0.64-1.93)

1.09 (0.62-1.92)

0.98 (0.54-1.77)

 Both

1.43 (1.03-1.98)

1.25 (0.88-1.80)

1.02 (0.69-1.52)

1.08 (0.71-1.64)

Age

0.98 (0.97-1.00)

0.99 (0.97-1.00)

0.98 (0.97-1.00)

Male gender

1.32 (0.98-1.79)

1.27 (0.93-1.75)

1.26 (0.90-1.77)

Race

 White

1.0

1.0

1.0

 Black

0.68 (0.48-0.97)

0.70 (0.48-1.01)

0.56 (0.38-0.84)

 Other

1.32 (0.49-3.56)

1.25 (0.42-3.73)

1.05 (0.34-3.26)

Marital Status

 Married/ live with partner

1.0

1.0

1.0

 Widow/Div/Sep

1.14 (0.81-1.60)

1.08 (0.76-1.54)

1.11 (0.76-1.61)

 Never married

0.96 (0.62-1.48)

0.90 (0.58-1.42)

0.88 (0.55-1.41)

Lifetime Depression

1.07 (0.73-1.57)

0.92 (0.61-1.40)

Anxiety^a

0.90 (0.56-1.42)

0.75 (0.45-1.27)

PTSD^b

0.88 (0.54-1.43)

0.85 (0.50-1.44)

Anhedonia

0.93 (0.65-1.34)

0.86 (0.57-1.29)

Recreational vs. no marijuana

OR (95%CI)

Medical vs. no marijuana

OR (95%CI)

Both medical and recreational vs. no marijuana

OR (95%CI)

Model 4: Full Adjusted Model

OR (95%CI)

Any SUD^c

3.13 (1.70-5.76)

3.07 (1.62-5.82)

Current Smoker

1.75 (1.19-2.58)

1.63 (1.09-2.45)

High pain severity

1.23 (0.82-1.84)

High pain interference

1.67 (1.12-2.48)

# Pain Sites

1.05 (1.00-1.10)

COMM^d

0.88 (0.58-1.32)

PODS^e

2.57 (1.56-4.24)

Vital Exhaustion

0.69 (0.40-1.19)

High Emotional Support^f

0.84 (0.60-1.18)

High Social Role Functioning^g

0.72 (0.44-1.17)