Fig. 1
From: DMSO potentiates the suppressive effect of dronabinol on sleep apnea and REM sleep in rats
Sleep efficiency quantified as a percentage of time spent asleep from 6 h recordings of conscious chronically-instrumented rat experiments. Vehicle (25% DMSO in PBS) or dronabinol (10 mg/kg) was injected IP in combination with vehicle or CB1 receptor (AM 251, 5 mg/kg) or CB2 receptor (AM 630, 5 mg/kg) antagonist, or both. There were no significant main effects. Data (mean ± SEM) were analyzed using linear mixed model analysis with repeated/fixed measures (CB agonist and CB antagonist)