Table 1 Analytical parameters of a GC-MS method for RSD (intraday and interday accuracy of repeated injections; %), LOD (limit of detection) and LOQ (limit of quantification) for cannabinoid internal standard (Cannabinoid Mixture 10; Cayman Chemical, Ann Arbor, MI, USA) injected three times at a concentration of 500 ng/mL

CBDV (mg/kg)

CBD (mg/kg)

CBG (mg/kg)

CBC (mg/kg)

Δ8-THC (mg/kg)

Repeat-1 @ 500 ng

0.55

0.56

0.56

0.55

0.55

Repeat-2 @ 500 ng

0.56

0.56

0.59

0.54

0.47

Repeat-3 @ 500 ng

0.50

0.68

0.51

0.51

0.46

Average

0.54

0.60

0.55

0.54

0.49

2xSD

0.07

0.13

0.08

0.04

0.10

RSD

6%

11%

7%

4%

10%

LOD^b

82.31

166.40

100.93

50.19

118.90

LOQ^b

274.36

554.65

336.42

167.30

396.32

Δ9-THC (mg/kg)

CBDA (mg/kg)

CBN (mg/kg)

CBGA (mg/kg)

THCA (mg/kg)

Repeat-1 @ 500 ng

0.54

0.44

0.56

0.45

Repeat-2 @ 500 ng

0.55

0.57

0.55

0.59

0.56

Repeat-3 @ 500 ng

0.46

0.51

0.49

0.56

0.49

Average

0.52

0.51

0.53

0.57

0.50

2 × SD

0.10

0.13

0.07

0.05

0.12

RSD

9%

13%

7%

4%

12%

LOD^b

122.37

164.20

88.90

56.49

144.68

LOQ^b

407.91

547.33

296.34

188.30

482.28