THC and CBD affect metabolic syndrome parameters including microbiome in mice fed high fat-cholesterol diet

Table 4 Effect of THC or CBD treatment on lipid and enzyme profile in mice fed HFCD

	ND	HF-C	HF-C CBD	HF-C THC
Cholesterol (mg/dl)	121.29 ± 5.73b	159.17 ± 3.94a	178.17 ± 9.31a	170.38 ± 3.9a
HDL cholesterol (mg/dl)	97.76 ± 3.76b	119.6 ± 4.2a	127.38 ± 9.05a	121.9 ± 3.09a
Triglycerides (mg/dl)	158 ± 14.05a	64.5 ± 5.4b	82 ± 3.59b	82.5 ± 2.89b
Alk Phos (μl/l)	90.67 ± 2.59a	77.33 ± 6.44ab	73.67 ± 3.69b	77.75 ± 1.6ab
SGOT (μl/l)	52 ± 5.47b	81.2 ± 4.91a	67.5 ± 6.47ab	72.25 ± 4.18a
SGPT (μl/l)	30.67 ± 5.08b	61.6 ± 10.25a	54.33 ± 7.74a	57.25 ± 7.69a

All values are expressed as mean ± SEM (n = 5). Values marked with different letters are significantly different (p < 0.05) in the Tukey–Kramer test
Alk Phos alkaline phosphatase, SGOT serum glutamic-oxaloacetic transaminase, SGPT serum glutamic pyruvic transaminase

ISSN: 2522-5782