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Table 2 IC50 values for CBD on a subset of the NaV channel isoforms

From: A nutraceutical product, extracted from Cannabis sativa, modulates voltage-gated sodium channel function

Isoform

IC50 value (μM)

n (cells)

NaV1.1

18.5 ± 2.2

9

NaV1.2

18.4 ± 2.6

6

NaV1.6

16.6 ± 1.8

7

NaV1.7

11.9 ± 2.2

7

  1. IC50 values are mean±SEM. IC50 half-maximal inhibitory concentration, CBD cannabidiol, NaV voltage-gated sodium
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Journal of Cannabis Research

ISSN: 2522-5782