Fig. 1
Inhalant cannabichromene (CBC) improved pulmonary function. A Treating mouse model of acute respiratory distress syndrome (ARDS) with inhalant CBC, specifically designed cone-shaped spout of the inhaling device (ApelinDxtm) connected to spacer completely sealed for a soft, comfortable, and insuring delivery of inhalant CBC to the mice. B Blood oxygen saturation was increased by ~8% towards a normal level (Blue bar) in mice treated with Poly (I:C) (PIC) followed by the treatment of inhalant CBC (PIC + CBC) (Green bar) compared to the untreated group (PIC) (Red bar) (**p<0.05, bars show means +/− standard deviation, SD). C Histological analysis, hematoxylin and eosin (H&E upper panels), and Masson’s trichrome (MT lower panels) demonstrated that Poly (I:C) caused the destruction of morphology and architecture of lung in mice with ARDS compared to the normal control group (sham). Inhalant CBC was able to improve the lung structure towards a normal status (PIC + CBC)