Table 2 Participant characteristics stratified by severity of balance disturbance
From: Cannabis use is not associated with increased balance disturbances in HIV-infected individuals
Variables | Moderate-severe Imbalance (n = 430) | No or minimal Imbalances (n = 3191) | Effect size (95% CI) | p value |
|---|---|---|---|---|
Demographics | ||||
Age (years), mean (SD) | 51.7 (10) | 44.8 (11) | 0.62 [0.52; 0.72]a | < .0001 |
Education, mean (SD) | 12.9 (3) | 13.0 (3) | − 0.03 [− 0.13; 0.06]a | 0.756 |
Male, n (%) | 306 (71.2) | 2504 (78.5) | 0.67 [0.54; 0.84]b | < .0006 |
Ethnicity, n (%) | ||||
Hispanic | 54 (12.6) | 590 (18.5) | 0.04 | |
Non-Latino white | 216 (50.2) | 1524 (47.8) | ||
African American | 144 (33.5) | 949 (29.7) | ||
Asian | 4 (0.9) | 33 (1.0) | ||
Other | 12 (2.8) | 95 (3.0) | ||
BMI (kg/m2), mean (SD) | 27.9 (7) | 26.9 (9) | 0.10 [0.00; 0.20]a | 0.006 |
Cannabis use, n (%) | ||||
Urine toxicology positive for THC | 63 (14.9) | 451 (14.27) | 1.09 [0.82; 1.46]b | 0.5 |
Cannabis ever used, n (%) | 262 (73.8) | 1964 (74.4) | 1.03 [0.80; 1.32]b | 0.8 |
Lifetime years Cannabis use, mean (SD) | 9.7 (7.8) | 8.4 (6.8) | 0.12 [− 0.00; 0.25]a | 0.07 |
Lifetime Quantity Cannabis (grams), mean (SD) | 4871 (11573) | 4648 (12705) | 0.11 [0.01; 0.14]a | 0.3 |
HIV serostatus, n (%) | ||||
HIV+ individuals | 384 (13.5) | 2462 (86.5) | ||
HIV− individuals | 42 (5.5) | 717 (94.6) | ||
Neurological disease, n (%) | ||||
cDSPN, n (%) | 303(70.5) | 1469 (46.0) | 2.79 [2.24; 3.47]b | < .0001 |
gait ataxia, n (%) | 54 (12.5) | 96 (3.0) | 0.2 [0.15; 0.30]b | < .0001 |
Medication currently used, n (%) | ||||
Opioids, n (%) | 132 (30.7) | 401 (12.6) | 3.08 [2.44; 3.87]b | < .0001 |
Sedatives, n (%) | 77 (17.9) | 327 (10.2) | 1.99 [1.51; 2.62]b | < .0001 |
Antihypertensives, n (%) | 52 (12.1) | 235 (7.4) | 1.77 [1.29; 2.44]b | < .0001 |