Fig. 4

Results of extinction training over a four day period following the original memory test in female mice. a. Extinction of the tone-associated memory was assessed in the novel context by recording freezing levels averaged across seven presentations of the auditory cue and comparing these levels within groups across days, and across treatment groups on the last day, with a t-test (*p = < 0.05). b.Contextual memory extinction was similarly assessed by averaging freezing levels over a five minute period in the original conditioning context (*p < 0.05). c. Extinction of generalized fear was similarly assessed by measuring freezing levels during a three minute baseline period in the novel context (*p < 0.05). The timeline for the experiment is shown in the inset above