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Table 4 limit of detection and limit of quantification for 5 common cannabinoids using both high performance liquid chromatography and gas chromatography for quantification. (Brighenti et al. 2017; Pellati et al. 2018)

From: Methods for quantification of cannabinoids: a narrative review

 

HPLC

 

GC-MS

 

Interest compound

LODb (μg/ml)

LOQb (μg/ml)

LODb (μg/ml)

LOQb (μg/ml)

CBDa

0.20

0.60

0.17

0.56

THCa

0.15

0.47

0.16

0.54

CBGa

0.18

0.54

N/A

N/A

CBNa

0.10

0.31

0.12

0.39

CBCa

0.18

0.53

N/A

N/A

  1. aCBD cannabidiol, THC tetrahydrocannabinol, CBG cannabigerol, CBN Cannabinol, CBC Cannabichromene
  2. b LOD limit of detection, LOQ limit of quantification