Skip to main content

Table 1 Up-regulated genes of interest (GOIs) after exposure of HSAEpC to various dilutions of cannabis oil extract for 24 h

From: Effects of cannabis oil extract on immune response gene expression in human small airway epithelial cells (HSAEpC): implications for chronic obstructive pulmonary disease (COPD)

SymbolDescription1:400 Dil.1:800 Dil.1:1600 Dil.
Fold Change95% CIP-valueFold Change95% CIP-valueFold Change95% CIP-value
BCL6B-cell leukemia/lymphoma 62.408(1.94, 2.88)0.00006      
CCL22Chemokine (C-C motif) ligand 225.309(2.69, 7.93)0.000455.249(2.83, 7.67)0.00022   
CCL24Chemokine (C-C motif) ligand 2459.800(42.54, 77.06)< 0.00001      
CCL26Chemokine (C-C motif) ligand 265.396(3.50, 7.29)< 0.00001      
CSF2Colony stimulating factor 2 (granulocyte-macrophage)148.914(118.08, 179.74)< 0.0000147.615(39.28, 55.95)< 0.000014.018(3.33, 4.70)< 0.00001
IL4Interleukin 48.696(6.26, 11.13)0.0000112.324(9.57, 15.08)< 0.000013.679(2.41, 4.95)0.00038
IL12AInterleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)6.789(2.15, 11.43)0.00048      
IL12BInterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)5.196(0.00001, 10.54)0.03230      
IL13RA2Interleukin 13 receptor, alpha 219.244(16.80, 21.69)< 0.0000123.779(21.19, 26.37)< 0.000015.049(4.19, 5.91)< 0.00001
IL17AInterleukin 17A33.457(21.68, 45.24)0.0000435.543(25.63, 45.46)< 0.000017.563(5.64, 9.49)< 0.00001
IL1RL1Interleukin 1 receptor-like 1180.497(122.94, 238.06)< 0.00001161.270(105.45, 217.09)< 0.000017.296(4.95, 9.64)< 0.00001
PPARGPeroxisome proliferator-activated receptor gamma5.415(4.81, 6.02)< 0.000017.367(6.40, 8.34)< 0.000013.004(2.63, 3.38)< 0.00001
PRG2Proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)   2.600(2.04, 3.16)0.00004   
PTGDR2Prostaglandin D2 receptor 23.725(1.55, 5.90)0.00374      
TBX21T-box 2128.785(23.31, 34.26)< 0.00001      
TSLPThymic stromal lymphopoietin11.999(9.61, 14.39)< 0.000012.602(2.03, 3.18)0.00002