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Fig. 5 | Journal of Cannabis Research

Fig. 5

From: Anticancer properties of cannabidiol and Δ9-tetrahydrocannabinol and synergistic effects with gemcitabine and cisplatin in bladder cancer cell lines

Fig. 5

Assessment of synergy between Δ9-tetrahydrocannabinol or cannabidiol and chemotherapeutic agents. Concentration-response curves of Δ9-THC or CBD combined with different concentrations of chemotherapeutic agents from the matrix are presented in T24 cells. A Gemcitabine with selected concentrations of Δ9-THC. B Cisplatin with selected concentrations of Δ9-THC. C Gemcitabine:cisplatin with selected concentrations of Δ9-THC. D Gemcitabine with selected concentrations of CBD. E Cisplatin with selected concentrations of CBD. F Gemcitabine:cisplatin with selected concentrations of CBD. X-axis intervals increase by a value of 2. Hollow points represent each drug’s effects alone. Red boxes indicate the concentrations where combinations of drugs were found to be synergistic as determined by the bliss independence model using SynergyFinder 2.0 software and significantly different from Δ9-THC, CBD, or chemotherapeutic treatment alone

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Journal of Cannabis Research

ISSN: 2522-5782