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Fig. 5 | Journal of Cannabis Research

Fig. 5

From: C. elegans as a test system to study relevant compounds that contribute to the specific health-related effects of different cannabis varieties

Fig. 5

Effect of polar fractions (PFs) of different varieties on the avoidance of a noxious smell. The effect of the polar fractions (PFs) on the nervous system was assessed by the effect on the time of one full reversal backwards movement of 1-octanol treated C. elegans exposed to 100 μg/mL PFs of different varieties. Treatment with PF of varieties: MGC 1003, MGC 1007, MGC 1009, MGC 1013, MGC 1027, MGC 1046, MGC 1074, MGC 1122, and MGC 1101 all reduced the responsiveness of nematodes to the aversive odor 1-octanol. MQ indicates the Milli-Q water control group, DMSO (dimethyl sulfoxide) and ethanol the vehicle control. Mann-Whitney U tests were used to compare the vehicle control conditions (DMSO/ethanol) to the experimental conditions. Green bars denote the effect on avoidance by C. elegans exposed to PFs of different cannabis varieties; brown bars denote vehicles; *** = false discovery rate (FDR)-corrected p < .001; ** = FDR-corrected p < .01; * = FDR-corrected p < .05

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Journal of Cannabis Research

ISSN: 2522-5782