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Table 3 Crude and adjusted odd ration (OR) and 95% confidence interval from multivariable logistic regression of factors associated with the use of cannabidiol to treat childhood epilepsy

From: Survey of local cannabidiol use in parents of children with epilepsy in Thailand: the prevalence, perceptions, and knowledge

 

Used

n (%)

Never use

n (%)

Crude odds ratio

(95%CI)

p-value

Adjusted odds ratio*

(95%CI)

p-value

Sex

Female

5 (6.58)

71 (93.42)

1

 

1

 

Male

11 (12.22)

79 (87.78)

1.98 (0.66–5.97)

0.226

1.35 (0.33–5.53)

0.678

Age

Age (years), median (Min–Max)

11 (2–18)

12 (0.25–18)

0.96 (0.87–1.06)

0.411

0.88 (0.77–1.02)

0.083

Number previous ASMs

<3

1 (1.39)

71 (98.61)

1

 

1

 

3+

15 (15.96)

79 (84.04)

13.48 (1.74–104.66)

0.013

12.28 (1.27–118.8)

0.03

Median (Min–Max)

4 (1–6)

2 (0–7)

    

Income/month

0–50,000 baht

12 (8.16)

135 (91.84)

1

 

1

 

≥ 50,000 baht

4 (21.05)

15 (78.95)

3 (0.86–10.48)

0.085

1.67 (0.29–9.54)

0.562

Domicile

Central region

10 (9.09)

100 (90.91)

1

 

1

 

Rural area

6 (10.71)

50 (89.29)

1.2 (0.41–3.49)

0.738

0.66 (0.16–2.7)

0.565

Knowing cannabidiol in epilepsy

Yes

15 (18.52)

66 (81.48)

19.09 (2.46–148.26)

0.005

14.7 (1.43–150.87)

0.024

No

1 (1.18)

84 (98.82)

1

 

1

 

Knowing cannabidiol side effects

Yes

8 (44.44)

10 (55.56)

14 (4.34–45.17)

<0.001

12.73 (2.77–58.43)

0.001

No

8 (5.41)

140 (94.59)

1

 

1

 
  1. ASMs antiseizure medications
  2. *Adjusted for sex, child’s age, number of previous ASMs, income, domicile, knowing cannabidiol in epilepsy, and knowing cannabidiol side effects