Table 4 Effect of CBNT on differential white blood cell counts in mice
From: The effects of subacute exposure to a water-soluble cannabinol compound in male mice
Treatment group (mg/kg/d) | ||||||
|---|---|---|---|---|---|---|
Vehicle control (0) | 0.04 CBN | 0.1 CBN | 0.4 CBN | 1.0 CBN | 4.0 CBN | |
n | 8 | 6 | 8 | 9 | 8 | 7 |
Lymphocytes | ||||||
Mean ± SD | 5791 ± 2014 | 6139 ± 1867 | 4530 ± 2047 | 5162 ± 1261 | 4036 ± 1853 | 4578 ± 1023 |
% | 87.8 ± 7.2 | 92.3 ± 2.7 | 88.8 ± 7.3 | 93.3 ± 2.2 | 81.0 ± 32.8 | 91.9 ± 2.5 |
Neutrophils | ||||||
Mean ± SD | 253 ± 1404 | 278 ± 176 | 328 ± 190 | 197 ± 136 | 222 ± 133 | 241 ± 53 |
% | 3.9 ± 0.8 | 4.0 ± 2.2 | 8.0 ± 5.8 | 3.4 ± 2.0 | 4.4 ± 2.3 | 5.0 ± 1.5 |
Band cells | ||||||
Mean ± SD | 0 | 0 | 0 | 0 | 0 | 0 |
% | 0 | 0 | 0 | 0 | 0 | 0 |
Monocytes | ||||||
Mean ± SD | 285 ± 192 | 110 ± 130 | 155 ± 172 | 153 ± 69 | 80 ± 45 | 147 ± 81 |
% | 6.0 ± 7.3 | 1.6 ± 2.8 | 2.6 ± 2.8 | 2.6 ± 1.6 | 1.4 ± 1.0 | 2.1 ± 2.0 |
Eosinophils | ||||||
Mean ± SD | 101 ± 97 | 89 ± 119 | 0a | 21a ± 34 | 25a ± 27 | 6a ± 15 |
% | 1.6 ± 1.8 | 1.3 ± 1.6 | 0 | 0.3 ± 0.5 | 0.5 ± 0.5 | 0.1 ± 0.4 |
Basophils | ||||||
Mean ± SD | 0 | 0 | 0 | 0 | 0.9 ± 2.5 | 0 |
% | 0 | 0 | 0 | 0 | 0 | 0 |