Table 2 Effects of CBNT on body and organ weight in mice
From: The effects of subacute exposure to a water-soluble cannabinol compound in male mice
Treatment group (mg/kg/d) | ||||||
|---|---|---|---|---|---|---|
Vehicle control (0) n = 10 | 0.04 CBN n = 9 | 0.1 CBN n = 10 | 0.4 CBN n = 10 | 1.0 CBN n = 10 | 4.0 CBN n = 10 | |
Initial body weight (g ± SD) | 31.4 ± 2.9 | 31.2 ± 1.6 | 30.9 ± 2.5 | 31.8 ± 1.4 | 30.6 ± 2.2 | 29.9 ± 2.8 |
Weight change (g ± SD) | 2.0 ± 1.6 | 3.2 ± 1.1 | 3.4 ± 1.6 | 2.3 ± 1.2 | 2.7 ± 1.5 | 1.9 ± 1.2 |
Average liver weight (g ± SD) | 1.77 ± 0.14 | 1.73 ± 0.19 | 1.73 ± 0.22 | 1.71 ± 0.12 | 1.60 ± 0.17 | 1.52 ± 0.24 |
Average heart weight (g ± SD) | 0.16 ± 0.03 | 0.16 ± 0.01 | 0.18 ± 0.03 | 0.17 ± 0.02 | 0.17 ± 0.02 | 0.16 ± 0.02 |
Average R lung weight (g ± SD) | 0.17 ± 0.04 | 0.18 ± 0.02 | 0.18 ± 0.03 | 0.16 ± 0.03 | 0.19 ± 0.02 | 0.17 ± 0.04 |
Average L lung weight (g ± SD) | 0.09 ± 0.02 | 0.09 ± 0.02 | 0.09 ± 0.02 | 0.08 ± 0.03 | 0.10 ± 0.02 | 0.09 ± 0.02 |
Average R kidney weight (g ± SD) | 0.29 ± 0.02 | 0.30 ± 0.03 | 0.29 ± 0.04 | 0.29 ± 0.04 | 0.28 ± 0.03 | 0.27 ± 0.04 |
Average L kidney weight (g ± SD) | 0.28 ± 0.02 | 0.29 ± 0.03 | 0.28 ± 0.04 | 0.28 ± 0.04 | 0.28 ± 0.02 | 0.27 ± 0.05 |