Fig. 6

Assessment of synergy between cannflavin A and cannabinoids. Cell viability of T24 (A, C, E, G) and TCCSUP (B, D, F, H) cells following treatment with Δ9-tetrahydrocannabinol (A and B), cannabidiol (C and D), cannabichromene (E and F), or cannabivarin (G and H) combined with 0.411, 3.7, or 33.33 μM cannflavin A. The statistics indicate the significance of the addition of the various concentrations of cannflavin A compared to treatment with cannabinoids alone. In each graph, the effect of cannflavin A at 0.411, 3.7, or 33.33 μM cannflavin A is indicated by open data points (on the right of the graph). Results represent the means ± SEM of 3 experiments. *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001. Combinations with 3.7 and 33.33 μM cannflavin A were deemed most statistically significant