Fig. 5

Assessment of synergy between cannflavin A and chemotherapeutic agents. Cell viability of T24 (A, C, E) and TCCSUP (B, D, F) cells following treatment with gemcitabine (A and B) cisplatin (C and D) or cisplatin/gemcitabine (E and F) combined with 3.13, 12.5, or 50 μM cannflavin A. The statistics indicate the significance of the addition of the various concentrations of cannflavin A compared to treatment with chemotherapeutic agents alone. In each graph, the effect of cannflavin A at 3.13, 12.5, or 50 μM cannflavin A is indicated by open data points (on the right of the graph). Results represent the means ± SEM of 3 experiments. *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001