Fig. 2

Effects of cannflavin A on cell viability. A Cell viability was assessed after 48-h treatment with cannflavin A in T24 and TCCSUP cells. The results from Fig. 1A in T24 cells were used to compare with the TCCSUP cell line. The results indicate that both transitional cell carcinomas are sensitive to cannflavin A in a similar fashion. B Schematic representation of the structure of cannflavin A. C Effects of cannflavin A on the viability of primary bladder epithelial cells. The results indicate that cannflavin A becomes cytotoxic at a concentration of 100 μM, but concentrations below this level are not cytotoxic. Results are means ± SEM of at least 3 independent experiments