Fig. 3

Effect of THC or CBD treatment on liver and adipose tissue weight in mice fed HFCD. Male C57BL/6J mice aged 7–8 weeks were fed either normal diet (ND, n = 8), high fat + 1%(w/w) cholesterol + 0.5%(w/w) cholate diet (HF-C, n = 8), HFCD containing CBD (2.39 mg/kg) (HF-C CBD, n = 8), HFCD containing THC (2.5 mg/kg) (HF-C THC, n = 8). Liver (A) or adipose (B) tissue weight of mice at the conclusion of the experiment is expressed as mean ± SEM. Columns marked with different letters (a, b) are significantly different (p < 0.05) according to the Tukey–Kramer post hoc test