Cannabinoids in the management of behavioral, psychological, and motor symptoms of neurocognitive disorders: a mixed studies systematic review

Table 5 Summary of study parameters (alternative order based on quality ratings)

Abbreviations: AD (dementia) Alzheimer’s disease, AE adverse event, BDNF brain-derived neurotrophic factor, CGI Clinical Global Impression, Clin. Diag. clinical diagnosis, Cond. condition (diagnosis), CMAI Cohen-Mansfield Agitation Inventory, Diag. Guide diagnostic guide, DSM Diagnostic and Statistical Manual of Mental Disorders (version III or IV or IV-TR/Text Revision), Dyskin. dyskinesia, Eur. Europe, GAF Global Assessment of Functioning, HD Huntington’s disease, MMSE mini-mental state examination, N.A. North America, NINCDS-ADRDA National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer’s Disease and Related Disorders Association, NL Netherlands, NPI neuropsychiatric inventory, NPS neuropsychiatric symptoms, PD Parkinson’s disease, PAS Pittsburgh Agitation Scale, Plac placebo, Reg. region, RCT randomized controlled trial, S.A. South America, UPDRS Unified PD Rating Scale, UK United Kingdom, USA United States of America, Week week (treatment duration), Year year (of study); Studies are rated as ‘poor’ quality (< 14; yellow highlight), ‘fair’ quality (16-19; green highlight), and ‘good’ quality (20–28; blue highlights), with all quality rating based on the Modified Downs and Black Checklist (Appendix 2); Orange highlights: studies lacking a placebo treatment

ISSN: 2522-5782