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Fig. 1 | Journal of Cannabis Research

Fig. 1

From: Olivetolic acid, a cannabinoid precursor in Cannabis sativa, but not CBGA methyl ester exhibits a modest anticonvulsant effect in a mouse model of Dravet syndrome

Fig. 1

Pharmacokinetic analysis of CBGA methyl ester and olivetolic acid in the mouse plasma and brain samples. A Comparison of the chemical structure of cannabigerolic acid (CBGA) to those of CBGA methyl ester and olivetolic acid. Concentration-time curves for B CBGA methyl ester in the plasma and brain and C olivetolic acid in the plasma and brain following 10 mg/kg i.p. injections. Concentrations are depicted as both mass concentrations (left y-axis) and molar concentrations (right y-axis). Data are expressed as means ± SEM, with n = 4 per time point

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