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Fig. 2 | Journal of Cannabis Research

Fig. 2

From: A potential role for cannabichromene in modulating TRP channels during acute respiratory distress syndrome

Fig. 2

Inhalant cannabichromene (CBC) may interact with the endocannabinoid system through enhancement of transient receptor potential (TRP) cation channels. Immunohistochemical staining of lung tissues with A transient receptor potential cation channel subfamily A member 1 (TRPA1) and B the transient receptor potential cation channel subfamily V member 1 (TRPV1) with less affinity showed an increase in the expression level of TRPA1 and TRPV1 in lung tissues of CBC treated group (PIC + CBC) compared to normal sham or Poly (I:C) treated one (sham or PIC) (images are all ×630 and inner images are ×100 magnification) (**p<0.01, means +/-SD). The bar graphs demonstrate the quantified analysis of the staining using particle count and color intensity measurement in the ImageJ software version 1.53

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