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Table 4 Comparison of effects of SCRA and cannabis use as reported by 154 participants undergoing treatment for cannabis use in New South Wales, Australia

From: The use and effects of synthetic cannabinoid receptor agonists by New South Wales cannabis treatment clients

Self-reported effects/experiencesa SCRAs
(%)
(n = 82)
Cannabis
(%)
(n = 72)
OR 95% CI McNemar Test
p-value
Racing heart/irregular heartbeat 40.2 9.8 4.1 1.9–8.9  < 0.001
Nausea 37.8 9.8 3.9 1.8–8.4  < 0.001
Panic 37.8 17.1 2.2 1.1–4.2 0.016
Dizziness 35.4 9.8 3.6 1.7–8.0 0.001
Excessive Sweatiness 31.7 9.8 3.3 1.5–7.2 0.003
Hangover effect 31.7 12.2 2.6 1.3–5.4 0.011
Dream-like state 31.7 22.0 1.4 0.8–2.6 0.291
Chest pain 28.0 8.5 3.3 1.4–7.7 0.005
Hallucinations 28.0 7.3 3.8 1.6–9.4 0.002
Decreased appetite 25.6 15.9 1.6 0.8–3.2 0.229
Light headedness 24.4 11.0 2.2 1.0–4.9 0.061
Confusion/disorientation 24.4 9.8 2.5 1.1–5.7 0.036
Psychotic experiences 20.7 8.5 2.4 1.0–5.9 0.064
Headache 20.7 11.0 1.9 0.8–4.2 0.169
Paranoia 19.5 13.4 1.5 0.7–3.1 0.442
Decreased motor coordination 19.5 12.2 1.6 0.7–3.5 0.327
Decreased ability to function after use 18.3 15.9 1.2 0.6–2.4 0.851
Nervousness or anxiety 18.3 12.2 1.5 0.7–3.4 0.424
Feelings of personal isolation 18.3 14.6 1.3 0.6–2.7 0.701
Nausea or vomiting 18.3 19.5 0.9 0.5–1.9 1.000
Passed out after use of SCRAs 17.1 14.6 1.2 0.5–2.5 0.845
Felt antisocial after smoking 17.1 13.4 1.3 0.6–2.8 0.690
Slurred Speech 17.1 11.0 1.6 0.7–3.6 0.405
Ringing in the ears 17.1 12.2 1.4 0.6–3.2 0.541
Worried about meeting strangers 15.9 11.0 1.4 0.6–3.4 0.523
Depression 13.6 19.8 0.7 0.3–1.5 0.442
Convulsions 12.2 4.9 2.5 0.8–8.0 0.180
Feel more energetic 11.0 34.1 0.3 0.2–0.7 0.003
Increased ability to function after use 8.5 43.9 0.2 0.1–0.4  < 0.001
Felt sluggish/heavy 7.3 18.3 0.4 0.2–1.0 0.078
Clumsy 6.1 24.4 0.3 0.1–0.7 0.004
Drowsiness 4.9 29.3 0.2 0.1–0.5  < 0.001
Dry mouth 2.4 23.2 1.1 0.0–0.5  < 0.001
Impaired memory 2.4 23.2 0.1 0.0–0.5  < 0.001
Felt more focused than usual 1.2 57.3 0.0 0.0–0.2  < 0.001
  1. aEvery item has four response options (1 = never, 2 = sometimes, 3 = most of the time, 4 = every time), with each answer categorised into ‘effect absent’ for never responses and ‘effect present’ for sometimes, most of the time and always