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Table 4 Comparison of effects of SCRA and cannabis use as reported by 154 participants undergoing treatment for cannabis use in New South Wales, Australia

From: The use and effects of synthetic cannabinoid receptor agonists by New South Wales cannabis treatment clients

Self-reported effects/experiencesa

SCRAs

(%)

(n = 82)

Cannabis

(%)

(n = 72)

OR

95% CI

McNemar Test

p-value

Racing heart/irregular heartbeat

40.2

9.8

4.1

1.9–8.9

 < 0.001

Nausea

37.8

9.8

3.9

1.8–8.4

 < 0.001

Panic

37.8

17.1

2.2

1.1–4.2

0.016

Dizziness

35.4

9.8

3.6

1.7–8.0

0.001

Excessive Sweatiness

31.7

9.8

3.3

1.5–7.2

0.003

Hangover effect

31.7

12.2

2.6

1.3–5.4

0.011

Dream-like state

31.7

22.0

1.4

0.8–2.6

0.291

Chest pain

28.0

8.5

3.3

1.4–7.7

0.005

Hallucinations

28.0

7.3

3.8

1.6–9.4

0.002

Decreased appetite

25.6

15.9

1.6

0.8–3.2

0.229

Light headedness

24.4

11.0

2.2

1.0–4.9

0.061

Confusion/disorientation

24.4

9.8

2.5

1.1–5.7

0.036

Psychotic experiences

20.7

8.5

2.4

1.0–5.9

0.064

Headache

20.7

11.0

1.9

0.8–4.2

0.169

Paranoia

19.5

13.4

1.5

0.7–3.1

0.442

Decreased motor coordination

19.5

12.2

1.6

0.7–3.5

0.327

Decreased ability to function after use

18.3

15.9

1.2

0.6–2.4

0.851

Nervousness or anxiety

18.3

12.2

1.5

0.7–3.4

0.424

Feelings of personal isolation

18.3

14.6

1.3

0.6–2.7

0.701

Nausea or vomiting

18.3

19.5

0.9

0.5–1.9

1.000

Passed out after use of SCRAs

17.1

14.6

1.2

0.5–2.5

0.845

Felt antisocial after smoking

17.1

13.4

1.3

0.6–2.8

0.690

Slurred Speech

17.1

11.0

1.6

0.7–3.6

0.405

Ringing in the ears

17.1

12.2

1.4

0.6–3.2

0.541

Worried about meeting strangers

15.9

11.0

1.4

0.6–3.4

0.523

Depression

13.6

19.8

0.7

0.3–1.5

0.442

Convulsions

12.2

4.9

2.5

0.8–8.0

0.180

Feel more energetic

11.0

34.1

0.3

0.2–0.7

0.003

Increased ability to function after use

8.5

43.9

0.2

0.1–0.4

 < 0.001

Felt sluggish/heavy

7.3

18.3

0.4

0.2–1.0

0.078

Clumsy

6.1

24.4

0.3

0.1–0.7

0.004

Drowsiness

4.9

29.3

0.2

0.1–0.5

 < 0.001

Dry mouth

2.4

23.2

1.1

0.0–0.5

 < 0.001

Impaired memory

2.4

23.2

0.1

0.0–0.5

 < 0.001

Felt more focused than usual

1.2

57.3

0.0

0.0–0.2

 < 0.001

  1. aEvery item has four response options (1 = never, 2 = sometimes, 3 = most of the time, 4 = every time), with each answer categorised into ‘effect absent’ for never responses and ‘effect present’ for sometimes, most of the time and always