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Table 2 Percent completing M6 and probability of retention at M3 and M6 by baseline prescription drug use and quality of life (QOL) in 1011 participants

From: The impact of non-medical cannabis legalization and other exposures on retention in longitudinal cannabis research: a survival analysis of a prospective study of Canadian medical cannabis patients

Baseline prescription drug use and QOL Completed M6 (%) Kaplan–Meier estimator
Probability of remaining in study
M3 M6 P
Use of opioid     0.004
  No 306/697 (43.9) 0.74 0.44  
  Yes 102/290 (35.2) 0.66 0.35  
Opioid – defined daily dose (DDD)     0.321
  < 0.57 44/108 (40.7) 0.64 0.41  
  ≥ 0.57 34/108 (31.5) 0.66 0.31  
Use of non-opioid pain medications     0.721
  No 314/770 (40.8) 0.73 0.41  
  Yes 94/215 (43.7) 0.70 0.44  
Non-opioid pain medications—defined daily dose (DDD)     0.245
  < 0.43 37/76 (48.7) 0.72 0.49  
  ≥ 0.43 36/89 (40.4) 0.64 0.40  
Use of benzodiazepine     0.151
  No 375/918 (40.8) 0.71 0.41  
  Yes 32/67 (47.8) 0.82 0.48  
Benzodiazepine–defined daily dose (DDD)     0.151
  < 0.38 13/29 (44.8) 0.71 0.41  
  ≥ 0.38 15/27 (55.6) 0.82 0.48  
Use of antidepressant     0.011
  No 324/818 (39.6) 0.71 0.40  
  Yes 83/166 (50.0) 0.78 0.50  
Antidepressant—defined daily dose (DDD)     0.342
  < 1 14/35 (40.0) 0.74 0.40  
  ≥ 1 45/90 (50.0) 0.78 0.50  
Use of anti-seizure     0.003
  No 326/827 (39.4) 0.71 0.39  
  Yes 83/159 (52.2) 0.79 0.52  
Anti-seizure—defined daily dose (DDD)     0.542
  < 0.5 24/46 (52.2) 0.80 0.52  
  ≥ 0.5 34/72 (47.2) 0.75 0.47  
WHOQOL—physical health (baseline)     0.671
  < 36 218/526 (41.4) 0.74 0.41  
   ≥ 36 199/481 (41.4) 0.70 0.41  
WHOQOL—psychological (baseline)     0.042
  < 54 166/442 (37.6) 0.71 0.38  
   ≥ 54 251/565 (44.4) 0.73 0.44  
WHOQOL—social relationships (baseline)     0.168
  < 58 147/384 (38.3) 0.71 0.38  
  ≥ 58 270/623 (43.3) 0.72 0.43  
WHOQOL—environment (baseline)     0.166
   < 66 222/556 (39.9) 0.70 0.40  
  ≥ 66 195/451 (43.2) 0.75 0.43  
  1. M3 = month 3 timepoint, M6 = month 6 timepoint