Table 1 Monitored transitions (m/z) for Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) standards in methanol, optimized using the Agilent MassHunter Optimization software for liquid chromatography tandem mass spectrometry (LC–MS/MS). Retention times were established in the chromatography separation
Drug | Associated Internal Standard (ISTD) | m/z Q1 | m/z Q3 | Retention Time (Minutes) |
|---|---|---|---|---|
CBD | CBD-d3 | 315.2 | 315.2 → 123 315.2 → 193 | 8.22 |
THC | THC-d3 | 315.2 | 315.2 → 123 315.2 → 193 | 9.13 |