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Table 3 Direct and specific indirect effects of youth demographics, psychological constructs of sensation-seeking, internalizing, and externalizing, and age at first use on lifetime tobacco and cannabis use status

From: Predictors of cannabis and tobacco co-use in youth: exploring the mediating role of age at first use in the population assessment of tobacco health (PATH) study

Variables Direct effect B (SE) 95% CI OR 95% CI
Co-use (as compared to single substance use)
→ Age at first use − 1.54 (0.09)* − 1.71, − 1.37 0.21 0.18, 0.25
→ Internalizing 0.18 (0.03)* 0.12, 0.24 1.20 1.12, 1.27
→ Externalizing 0.30 (0.05)* 0.20, 0.40 1.35 1.22, 1.50
→ Sensation seeking 0.15 (0.01)* 0.13, 0.17 1.16 1.14, 1.19
→ Grade 0.66 (0.02)* 0.62, 0.71 1.94 1.85, 2.03
→ Sex − 0.17 (0.06)* − 0.29, − 0.06 0.84 0.75, 0.94
→ Hispanic − 0.27 (0.07)* − 0.40, − 0.13 0.77 0.67, 0.88
→ Race − 0.04 (0.04) − 0.11, 0.03 0.96 0.89, 1.03
Age at first use
→ Internalizing − 0.11 (0.04)* − 0.20, − 0.03 0.89 0.82, 0.97
→ Externalizing − 0.21 (0.05)* − 0.31, − 0.11 0.81 0.73, 0.90
→ Sensation seeking − 0.07 (0.02)* − 0.10, − 0.03 0.94 0.91, 0.97
→ Grade 0.58 (0.03)* 0.52, 0.64 1.78 1.68, 1.89
→ Sex 0.32 (0.07)* 0.18, 0.45 1.37 1.20, 1.57
→ Hispanic 0.13 (0.08) − 0.03, 0.28 1.14 0.97, 1.32
→ Race − 0.10 (0.04)* − 0.18, − 0.02 0.91 0.84, 0.98
Through age at first use Indirect effect B (SE) 95% CI   
→ Internalizing 0.17 (0.07)* 0.05, 0.30
→ Externalizing 0.33 (0.08)* 0.16, 0.49
→ Sensation seeking 0.10 (0.03)* 0.05, 0.15
  1. Data are from the Population Assessment of Tobacco Health (PATH) study. *p < 0.05