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Table 4 Patents on medical cannabis upstream technologies (in planta genetic engineering)

From: Trends in intellectual property rights protection for medical cannabis and related products

Title

Short description

Patent doc. number

Plants and methods for increasing and decreasing synthesis of cannabinoids (US20200181631A1 - Plants and methods for increasing and decreasing synthesis of cannabinoids - Google Patents n.d.)

CRISPR/Cas9 system gene editing system to alter the expression of cannabinoids in plants

US20200181631A

Modulation of cannabinoid profile in cannabis (WO2020035869A1 - Modulation of cannabinoid profile in cannabis - Google Patents n.d.)

Gene editing technology to modify metabolite pathways in the cannabis plant or cells

WO2020035869A1

Systems and methods for enhancing trichome formation and density in cannabis (US20190352662A1 - Systems and methods for enhancing trichome formation and density in cannabis - Google Patents n.d.)

Insertion of heterologous genetic material to create a plant with upregulated trichome formation

US20190352662A1

Trichome specific promoters for the manipulation of cannabinoids and other compounds in glandular trichomes (US20190225975A1 - Trichome specific promoters for the manipulation of cannabinoids and other compounds in grandular trichomes - Google Patents n.d.)

Glandular trichomes of the cannabis plants are genetically engineered to produce cannabinoids in Cannabis sativa, and also in Nicotiana. tabacum

US20190225975A1