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Table 3 Patents on medical cannabis upstream technologies (ex planta genetic engineering)

From: Trends in intellectual property rights protection for medical cannabis and related products

Title

Short description

Patent doc. number

Chemical engineering processes and apparatus for the synthesis of compounds (US20200048664A1 - Chemical engineering processes and apparatus for the synthesis of compounds - Google Patents n.d.)

Methods and a system for producing cannabinoids and cannabinoid analogs via enzymatic reactions

US20200048664A1

Bioenzymatic synthesis of THC-v, CBV and CBN and their use as therapeutic agents (US10538790B2 - Bioenzymatic synthesis of THC-v, CBV and CBN and their use as therapeutic agents - Google Patents n.d.)

Methods for bio-enzymatic synthesizing of THC-v, CBV, and CBN

US10538790

Biosynthesis of cannabinoid prodrugs and their use as therapeutic agents (US20190382814A1 - Biosynthesis of cannabinoid prodrugs and their use as therapeutic agents - Google Patents n.d.)

Methods for producing cannabinoid prodrugs and a system for the large-scale production of the prodrugs

US20190382814A1

Apparatus, methods and composition for synthesis of cannabinoid compounds (US20190382708A1 - Apparatus, methods and composition for synthesis of cannabinoid compounds - Google Patents n.d.)

Systems and methods for producing a cannabinoid product with cannabinoid synthase in an immiscible phase

US20190382708A1

Microorganisms and methods for the fermentation of cannabinoids (WO2019071000A1 - Microorganisms and methods for the fermentation of cannabinoids - Google Patents n.d.)

Methods for synthesizing cannabigerolic acid (CBGA) and other cannabinoids in bacterial systems

WO2019071000A1

Production of cannabinoids in yeast (WO2019014490A1 - Production of cannabinoids in yeast - Google Patents n.d.)

Genetically modified yeast with GPP pathway genes, olivetolic acid producing genes, cannabinoid precursor or cannabinoid producing genes, or hexanoyl-CoA-producing genes

WO2019014490A1

Generation of water-soluble cannabinoid compounds in yeast and plant cell suspension cultures and compositions of matter (US20190078168A1 - Generation of Water-Soluble Cannabinoid Compounds in Yeast and Plant Cell Suspension Cultures and Compositions of Matter - Google Patents n.d.)

Systems, methods, and compositions for the generation of water-soluble cannabinoids in yeast, and other plant cell suspension cultures

US20190078168A1

Microbial engineering for the production of cannabinoids and cannabinoid precursors (WO2017139496A1 - Microbial engineering for the production of cannabinoids and cannabinoid precursors - Google Patents n.d.)

Compositions and methods for producing cannabinoids and cannabinoid precursors in microorganisms from a carbohydrate source

WO2017139496A1

Production of cannabinoids in microorganisms from a carbon sugar precursor (US20190382813A1 - Production of cannabinoids in microorganisms from a carbon sugar precursor - Google Patents n.d.)

A method for biosynthetic production of cannabinoids in microorganisms from a carbon source precursor

US20190382813A1

Biological composition based on engineered Lactobacillus paracasei subsp. paracasei f19 for the biosynthesis of cannabinoids (EP3067058A1 - Biological composition based on engineered lactobacillus paracasei subsp. paracasei f19 for the biosynthesis of cannabinoids - Google Patents n.d.)

A method for producing therapeutic cannabinoids characterized by administering to a host the probiotic Lactobacillus Paracasei subsp. Paracasei F19, genetically modified to produce and secrete cannabinoids from Cannabis sativa

EP3067058A1

Cannabinoid production in algae (WO2019202510A1 - Cannabinoid production in algae - Google Patents n.d.)

A system and method for producing a cannabinoid in genetically modified algae expressing several metabolic enzymes

WO2019202510A1