Fig. 1
From: Cannabis sativa extracts protect LDL from Cu2+-mediated oxidation
Mechanism of unsaturated fatty acid oxidation. In the first step, the unsaturated fatty acid (LH) is attacked by an oxidant (Ox●), abstracting a bis-allylic hydrogen and giving rise to an alkyl radical (L●), this radical can react with O2 generating a peroxyl radical (LOO●). The propagation phase is triggered and perpetuated by the reaction of L● and LOO● with reduced lipid molecules. Antioxidants (XH) can act preventing the initiation step or participating in the termination phase of lipid oxidation