Table 4 Multivariate analysis results of differences of key characteristics of 56,860 patients seeking medical cannabis certification by gender and age, with and without interaction
From: Medical cannabis use in the United States: a retrospective database study
| Â | Model without interaction between age and gender | Model with interaction between age and gender | ||
|---|---|---|---|---|
Characteristic | Coefficient (95% CI) | p-value | Coefficient (95% CI) | p-value |
Smoking Status | ||||
 Intercept | −0.890 (− 0.961, − 0.820) | < 0.001 | −1.00 (−1.108, − 0.900) | < 0.001 |
 Age | − 0.014 (− 0.016, − 0.013) | < 0.001 | − 0.012 (− 0.014, − 0.010) | < 0.001 |
 Gender (male) | 0.110 (0.066, 0.153) | < 0.001 | 0.294 (0.163, 0.426) | < 0.001 |
 Interaction | NA | NA | − 0.004 (− 0.007, − 0.001) | 0.004 |
Alcohol Consumption | ||||
 Intercept | −0.368 (− 0.424, − 0.311) | < 0.001 | −0.220 (− 0.302, − 0.138) | < 0.001 |
 Age | 0.002 (0.001, 0.003) | < 0.001 | − 0.001 (− 0.003, 0.000) | 0.108 |
 Gender (male) | − 0.066 (− 0.100, − 0.032) | < 0.001 | −0.312 (− 0.417, − 0.207) | < 0.001 |
 Interaction | NA | NA | 0.005 (0.003, 0.007) | < 0.001 |
Previous Cannabis Experience | ||||
 Intercept | 0.904 (0.844, 0.964) | < 0.001 | 0.992 (0.905, 1.08) | < 0.001 |
 Age | −0.004 (− 0.006, − 0.003) | < 0.001 | − 0.006 (− 0.008, − 0.005) | < 0.001 |
 Gender (male) | 0.143 (0.107, 0.179) | < 0.001 | − 0.005 (− 0.117, 0.107) | 0.929 |
 Interaction | NA | NA | 0.003 (0.001, 0.005) | 0.006 |
History of Substance Abuse | ||||
 Intercept | −2.540 (−2.664, −2.418) | < 0.001 | −2.284 (−2.475, −2.095) | < 0.001 |
 Age | −0.012 (− 0.015, − 0.010) | < 0.001 | −0.018 (− 0.022, − 0.014) | < 0.001 |
 Gender (male) | 0.361 (0.284, 0.439) | < 0.001 | −0.019 (− 0.249, 0.212) | 0.871 |
 Interaction | NA | NA | 0.009 (0.004, 0.014) | 0.001 |
Medication Usage | ||||
 Intercept | −1.014 (− 1.072, − 0.957) | < 0.001 | −0.595 (− 0.677, − 0.513) | < 0.001 |
 Age | 0.024 (0.023, 0.025) | < 0.001 | 0.015 (0.013, 0.017) | < 0.001 |
 Gender (male) | −0.607 (− 0.642, − 0.573) | < 0.001 | − 1.336 (− 1.445, − 1.227) | < 0.001 |
 Interaction | NA | NA | 0.016 (0.013, 0.018) | < 0.001 |
Average Number of Medications | ||||
 Intercept | 0.236 (0.214, 0.259) | < 0.001 | 0.356 (0.324, 0.389) | < 0.001 |
 Age | 0.011 (0.011, 0.012) | < 0.001 | 0.009 (0.008, 0.009) | < 0.001 |
 Gender (male) | −0.233 (− 0.247, − 0.220) | < 0.001 | −0.432 (− 0.473, − 0.391) | < 0.001 |
 Interaction | NA | NA | 0.004 (0.003, 0.005) | < 0.001 |
Average Number of Conditions | ||||
 Intercept | 1.483 (1.469, 1.497) | < 0.001 | 1.507 (1.487, 1.527) | < 0.001 |
 Age | 0.000 (0.000, 0.000) | 0.423 | −0.001 (− 0.001, 0.000) | 0.003 |
 Gender (male) | −0.143 (− 0.151, − 0.135) | < 0.001 | −0.183 (− 0.209, − 0.157) | < 0.001 |
 Interaction | NA | NA | 0.001 (0.000, 0.001) | 0.001 |