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Table 3 Physiological response to various inhaled doses of THC

From: Smokeless consumption of medical cannabis pharmacokinetics, safety and feasibility of the CannaHALER© a phase 1a study

 

Group I

10 ± 0.1 mg

Group II

15 ± 0.1 mg

Group III

20 ± 0.1 mg

Group IV

25 ± 0.1 mg

SBP (mmHg)

113.4 ± 10.23

114.93 ± 6.88

120.14 ± 28.03

130 ± 16.62

DBP (mmHg)

69.46 ± 7.86

63.85 ± 9.78

71.78 ± 14.95

80.57 ± 8.92

HR

71.66 ± 10.14

79 ± 13.37

68.35 ± 5.83

77.57 ± 17.74

SO2 (%)

99.93 ± 0.25

100

99.92 ± 0.26

99.42 ± 0.9

  1. All four THC dosage groups showed no significant change in physiological parameters measured during the study, parameters such as systolic and diastolic blood pressure, heart rate and oxygen saturation
  2. SBP systolic Blood pressure, DBP Diastolic Blood pressure, HR Heart Rate, SO2 Blood Oxygen saturation