Effects of cannabis oil extract on immune response gene expression in human small airway epithelial cells (HSAEpC): implications for chronic obstructive pulmonary disease (COPD)

Table 3 Evaluation of GOIs using the DAVID functional analytical tool

Gene Symbol	Disease-related GOI			Functional Analysis GOI			Biological Process GOI		Molecular Function GOI		Cellular Component GOI		KEGG Pathway GOI
Gene Symbol	COPD	Asthma	Asthma Bronchiolitis Viral/RSV	Cytokine Function	Signaling Function	Inflammatory Response Function	Immune Response	Positive Regulation of Inflammatory Response	Cytokine Activity	Cytokine Receptor Activity	Extracellular Space	Extracellular Region	Cytokine-Cytokine Receptor Interaction	Jak-STAT Signaling Pathway
ADRB2	X	X	X
AREG				X	X				X
BCL6	X					X		X
CCL22			X	X	X		X	X			X	X
CCL24		X	X	X	X	X	X	X			X
CCL26		X	X	X	X	X	X	X			X
CCL5	X	X	X	X	X	X	X	X			X	X	X
CLCA1		X			X						X
CMA1		X			X		X					X
CSF2	X	X	X	X	X		X		X		X		X	X
EPX					X						X
FOXP3		X	X
IL4	X	X	X	X	X		X		X		X	X	X	X
IL4R	X	X	X		X		X			X	X		X	X
IL5		X	X	X			X	X	X		X	X	X	X
IL12A	X	X	X	X	X		X		X		X	X	X	X
IL12B	X	X	X	X	X				X	X	X	X	X	X
IL13RA1		X	X		X					X			X	X
IL13RA2			X		X					X	X	X		X
IL17A		X	X	X	X		X	X	X		X	X	X
IL1RL1		X			X		X			X
IL33		X		X					X		X	X
LTB4R							X	X
MMP9	X	X			X						X	X
PMCH					X							X
POSTN					X						X
PPARG	X	X
PTGDR2		X					X
SATB1					X
STAT5A			X											X
TBX21		X	X
TNFSF4				X			X		X		X		X
TSLP		X		X	X				X		X		X	X
GOI Count	10	22	17	14	22	4	15	8	10	5	19	12	11	10

ISSN: 2522-5782