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Table 2 Down-regulated GOIs after exposure of HSAEpC to various dilutions of cannabis oil extract for 24 h

From: Effects of cannabis oil extract on immune response gene expression in human small airway epithelial cells (HSAEpC): implications for chronic obstructive pulmonary disease (COPD)

Symbol Description 1:400 Dil. 1:800 Dil. 1:1600 Dil.
Fold Change 95% CI P-value Fold Change 95% CI P-value Fold Change 95% CI P-value
ADRB2 Adrenergic receptor, beta 2 0.462 (0.40, 0.53) 0.00001       
AREG Amphiregulin 0.476 (0.41, 0.54) < 0.00001       
CCL5 Chemokine (C-C motif) ligand 5 0.226 (0.10, 0.36) 0.00119       
CLCA1 Chloride channel accessory 1 0.129 (0.03, 0.23) 0.02891 0.162 (0.06, 0.26) 0.03048    
CMA1 Chymase 1, mast cell 0.068 (0.04, 0.10) 0.00037 0.353 (0.20, 0.50) 0.00421    
EPX Eosinophil peroxidase 0.037 (0.03, 0.04) < 0.00001 0.213 (0.11, 0.31) < 0.00001    
FOXP3 Forkhead box P3 0.257 (0.12, 0.40) 0.00038       
IL3RA Interleukin 3 receptor, alpha (low affinity)     0.344 (0.16, 0.52) 0.00364    
IL4R Interleukin 4 receptor 0.261 (0.24, 0.28) < 0.00001       
IL5 Interleukin 5 (colony-stimulating factor, eosinophil) 0.319 (0.06, 0.58) 0.01014       
IL13RA1 Interleukin 13 receptor, alpha 1 0.343 (0.29, 0.40) < 0.00001       
IL33 Interleukin 33 0.185 (0.16, 0.21) < 0.00001       
LTB4R Leukotriene B4 receptor 0.194 (0.16, 0.23) < 0.00001 0.451 (0.39, 0.52) 0.00001    
MAF V-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) 0.237 (0.20, 0.28) < 0.00001 0.330 (0.29, 0.37) 0.00001    
MMP9 Matrix metallopeptidase 9 (gelatinase B, 92 kDa gelatinase, 92 kDa type IV collagenase) 0.274 (0.22, 0.33) 0.00001       
PMCH Pro-melanin-concentrating hormone 0.271 (0.17, 0.37) 0.00188 0.087 (0.03, 0.14) 0.00047    
POSTN Periostin, osteoblast specific factor 0.176 (0.16, 0.19) < 0.00001       
RORC RAR-related orphan receptor C 0.180 (0.00001, 0.36) 0.02731       
SATB1 SATB homeobox 1 0.481 (0.31, 0.65) 0.00148       
STAT5A Signal transducer and activator of transcription 5A 0.328 (0.27, 0.38) 0.00001       
TNFSF4 Tumor necrosis factor (ligand) superfamily, member 4 0.197 (0.08, 0.31) < 0.00001