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Table 2 Down-regulated GOIs after exposure of HSAEpC to various dilutions of cannabis oil extract for 24 h

From: Effects of cannabis oil extract on immune response gene expression in human small airway epithelial cells (HSAEpC): implications for chronic obstructive pulmonary disease (COPD)

SymbolDescription1:400 Dil.1:800 Dil.1:1600 Dil.
Fold Change95% CIP-valueFold Change95% CIP-valueFold Change95% CIP-value
ADRB2Adrenergic receptor, beta 20.462(0.40, 0.53)0.00001      
AREGAmphiregulin0.476(0.41, 0.54)< 0.00001      
CCL5Chemokine (C-C motif) ligand 50.226(0.10, 0.36)0.00119      
CLCA1Chloride channel accessory 10.129(0.03, 0.23)0.028910.162(0.06, 0.26)0.03048   
CMA1Chymase 1, mast cell0.068(0.04, 0.10)0.000370.353(0.20, 0.50)0.00421   
EPXEosinophil peroxidase0.037(0.03, 0.04)< 0.000010.213(0.11, 0.31)< 0.00001   
FOXP3Forkhead box P30.257(0.12, 0.40)0.00038      
IL3RAInterleukin 3 receptor, alpha (low affinity)   0.344(0.16, 0.52)0.00364   
IL4RInterleukin 4 receptor0.261(0.24, 0.28)< 0.00001      
IL5Interleukin 5 (colony-stimulating factor, eosinophil)0.319(0.06, 0.58)0.01014      
IL13RA1Interleukin 13 receptor, alpha 10.343(0.29, 0.40)< 0.00001      
IL33Interleukin 330.185(0.16, 0.21)< 0.00001      
LTB4RLeukotriene B4 receptor0.194(0.16, 0.23)< 0.000010.451(0.39, 0.52)0.00001   
MAFV-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)0.237(0.20, 0.28)< 0.000010.330(0.29, 0.37)0.00001   
MMP9Matrix metallopeptidase 9 (gelatinase B, 92 kDa gelatinase, 92 kDa type IV collagenase)0.274(0.22, 0.33)0.00001      
PMCHPro-melanin-concentrating hormone0.271(0.17, 0.37)0.001880.087(0.03, 0.14)0.00047   
POSTNPeriostin, osteoblast specific factor0.176(0.16, 0.19)< 0.00001      
RORCRAR-related orphan receptor C0.180(0.00001, 0.36)0.02731      
SATB1SATB homeobox 10.481(0.31, 0.65)0.00148      
STAT5ASignal transducer and activator of transcription 5A0.328(0.27, 0.38)0.00001      
TNFSF4Tumor necrosis factor (ligand) superfamily, member 40.197(0.08, 0.31)< 0.00001